You are here: Home News A bifunctional dipeptide can help to reduce pesticide use while preserving crop productivity
Date: May 09, 2019

A bifunctional dipeptide can help to reduce pesticide use while preserving crop productivity Alternative pest and disease control measures are needed to reduce pesticide use while preserving crop productivity. One of the innovative approach is to functionalize plant leaves to fight against most severe disease and increase stability of antimicrobial peptides against rain wash-off. A fusion of the antimicrobial peptide dermaseptin 01 and thanatin (DS01–THA) inhibits the germination of P. pachyrhizi spores in vitro and reduces Asian soybean rust (SBR) disease in a rainfast manner. The study shows that bifunctional peptides can be used to functionalize the crop surface for sustainable disease management.

Bonn, RWTH Aachen, Düsseldorf University and DWI Aachen scientists demonstrate that the bifunctional dipeptides can be used to functionalize crop surfaces for sustainable disease management.

Pesticides benefit society in many ways. They kill insects, weeds, microbes, and other potentially harmful organisms. They have a broad spectrum of application but their main utilization is in agriculture is to secure crop yield. However, some synthetic pesticides can also pose a threat to human health and the environment. Many of them succumb to wash off by rain and thus, need to be applied several times in a growing season. They can hit non-target species and drive the evolution of pesticide-insensitive insects, weeds, microbes, and other organisms that are hard to control. Although safer than ever, synthetic pesticides increasingly raise ecological and health concerns. Thus, an innovative approach was used as an alternative pest and disease control measures to reduce pesticide use while preserving crop productivity. Peptide-based adhesion promoters enable the immobilization of peptides or proteins and increase their binding strength on leaf surfaces. The fusion of the antimicrobial peptide dermaseptin 01 and thanatin inhibits the germination of P. pachyrhizi spores in vitro and reduces Asian soybean rust disease in a rainfast manner. Therefore, the study reveals that bifunctional peptides can be used to functionalize the crop surface for sustainable disease management.

Publications: “A bifunctional dermaseptin–thanatin dipeptide functionalizes the crop surface for sustainable pest management, Green Chemistry 21, 2316-2325, doi: 10.1039/c9gc00457b, Link: https://pubs.rsc.org/en/content/articlehtml/2019/GC/C9GC00457B” and a news article “Sticky pesticide could prevent harmful runoff, Science, 26 Apr 2019” doi: 10.1126/science.364.6438.318, Link: https://science.sciencemag.org/content/364/6438/318

Funding: The study was the scientific activities of the Bioeconomy Science Center and financially supported by the Ministry of Innovation, Science and Research in the NRW Strategy Project BioSC (No. 313/323-400-00213).

Contact: Dr. Shyam Pariyar, Horticultural Sciences Group, [Email protection active, please enable JavaScript.]

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